What drug classification is ibandronate?

Ibandronate is in a class of medications called bisphosphonates. It works by preventing bone breakdown and increasing bone density (thickness).

What is the medication BONIVA used for?

BONIVA is a prescription medicine used to treat or prevent osteoporosis in women after menopause. BONIVA helps increase bone mass and helps reduce the chance of having a spinal fracture (break).

What is the generic name of BONIVA?

Boniva is also available as a generic drug called ibandronate. Fosamax is available as a generic drug called alendronate.

What drug class is used for osteoporosis?

Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill.

What is the mechanism of action of Boniva?

Mechanism of Action

Ibandronate inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

What is the contraindications for Boniva?

Boniva is contraindicated in patients with the following conditions: Abnormalities of the esophagus which delay esophageal emptying such as stricture or achalasia. Inability to stand or sit upright for at least 60 minutes. Hypocalcemia.

What is the best bisphosphonate for osteoporosis?

Oral – We suggest alendronate or risedronate as the initial choice of oral bisphosphonate (table 1). We most commonly use alendronate, in part due to direct evidence showing residual fracture benefit in selected patients after completing a five-year course of therapy [1].

What is the mechanism of action of bisphosphonates?

Mechanism of action — The bisphosphonates inhibit osteoclastic bone resorption via a mechanism that differs from that of other antiresorptive agents [2-4]. Bisphosphonates attach to hydroxyapatite binding sites on bony surfaces, especially surfaces undergoing active resorption.

Why was Boniva taken off the market?

There are concerns about the long-term safety of bisphosphonates (such as Boniva) as long-term use has been associated with atypical femur fractures, osteonecrosis of the jaw, and esophageal cancer.

Why was Boniva taken off the market?

There are concerns about the long-term safety of bisphosphonates (such as Boniva) as long-term use has been associated with atypical femur fractures, osteonecrosis of the jaw, and esophageal cancer.

Does Boniva improve bone density?

Boniva is associated with significant increases in bone mineral density (BMD). This reduces the risk of fractures in osteoporosis patients.

What is the most common side effect of Boniva?

The most common side effects with the pill are diarrhea, pain in the extremities, and upset stomach. Less common side effects may be pain or trouble swallowing, heartburn and stomach ulcers.

Is Boniva a good drug for osteoporosis?

The bottom line. Fosamax, Prolia, and Boniva are all effective osteoporosis treatments since each one can help lower your risk of fractures.

How long should you take Boniva?

Boniva may be taken long term for osteoporosis. If your doctor determines that your risk of bone fracture is low, they may recommend that you stop taking Boniva after 3 to 5 years of treatment. This is because the safety and effectiveness of Boniva when taken for longer than 3 years isn’t known.

Can boniva cause kidney problems?

Severe kidney problems, including kidney failure, may happen when you take BONIVA. Your doctor should perform blood tests to check your kidneys before you receive each treatment.