What drug class is Cymbalta?

Duloxetine belongs to a group of medicines known as selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). These medicines are thought to work by increasing the activity of chemicals called serotonin and norepinephrine in the brain.

Is Cymbalta an SSRI or MAOI?

Cymbalta is classified in a group of medications called SNRIs (serotonin-norepinephrine reuptake inhibitors). They work by increasing the levels of serotonin and norepinephrine in the brain. Prozac is part of a group of drugs called SSRIs (selective serotonin reuptake inhibitors).

What is Cymbalta used to treat?

Descriptions. Duloxetine is used to treat depression and anxiety. It is also used for pain caused by nerve damage associated with diabetes (diabetic peripheral neuropathy).

What is Cymbalta mechanism of action?

Mechanism of Action

Cymbalta (duloxetine hydrochloride) is a oral dual reuptake inhibitor that enhances the levels of the neurotransmitters, serotonin and norepinephrine.

What drugs should not be taken with Cymbalta?

Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication.

How is Cymbalta different from other antidepressants?

Cymbalta is approved for some unique indications related to neuropathic and musculoskeletal pain. These indications set Cymbalta apart from other antidepressant medications as it is the only one approved in pain-related diagnoses.

Is Cymbalta a depressant or stimulant?

Cymbalta (duloxetine) is an antidepressant that has also been approved by the FDA to treat fibromyalgia, diabetic neuropathy (nerve damage) and long-term muscle pain.

What type of antidepressant is Cymbalta?

Cymbalta contains the active drug duloxetine. Duloxetine belongs to a drug class called serotonin-norepinephrine reuptake inhibitors (SNRIs).

What are the negative side effects of Cymbalta?

Common side effects

Headache, nausea, diarrhea, dry mouth, decreased appetite, increased sweating, feeling nervous, restless, fatigued, sleepy or having trouble sleeping (insomnia). These will often improve over the first week or two as you continue to take the medication.

Is Cymbalta an MAOI?

Cymbalta is not a MAOI inhibitor. It is a serotonin-norepinephrine reuptake inhibitor (SNRI) type of antidepressant.

Which antidepressants are MAOI?

MAOIs approved to treat depression
  • Isocarboxazid (Marplan)
  • Phenelzine (Nardil)
  • Selegiline (Emsam)
  • Tranylcypromine (Parnate)

What is the difference between a MAOI and a SSRI?

Although SSRIs are the current frontline treatment for depression, monoamine oxidase inhibitors (MAOIs) were the first antidepressants developed. They are typically more potent than SSRIs because they affect more neurotransmitters, and they can cause more side effects.

Does duloxetine have monoamine oxidase inhibitor?

Duloxetine has no significant affinity for dopaminergic, adrenergic, cholinergic, histaminergic, opioid, glutamate, and GABA receptors in vitro. Duloxetine does not inhibit monoamine oxidase (MAO).

Is Wellbutrin an MAOI or an SSRI?

Wellbutrin is an antidepressant medication commonly prescribed for the treatment of depression. Unlike many antidepressants that are SSRIs or SNRIs, Wellbutrin is an NDRI (norepinephrine and dopamine reuptake inhibitor).

Is Wellbutrin a MAOI?

Bupropion was originally classified as an “atypical” antidepressant because it does not exert the same effects as the classical antidepressants such as Monoamine Oxidase Inhibitors (MAOIs), Tricyclic Antidepressants (TCAs), or Selective Serotonin Reuptake Inhibitors (SSRIs).

What is most commonly prescribed MAOI?

The four most commonly prescribed MAOIs are selegiline, isocarboxazid, phenelzine, and tranylcypromine.

Is it OK to take Cymbalta and Wellbutrin together?

Combining these medications may increase the risk of seizures, which may occur rarely with either medication. In addition, buPROPion can increase the blood levels of DULoxetine, which may increase other side effects.

What drug class is Trazodone?

Trazodone is in a class of medications called serotonin modulators. It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.

Is Wellbutrin Adderall?

Are Wellbutrin and Adderall the same? No. Wellbutrin is an antidepressant, and Adderall is a stimulant. They have differences in dosing, pricing, side effects, and drug interactions.

Does Cymbalta help with energy?

Taking Cymbalta can improve mood, sleep, appetite and energy levels while also decreasing nervousness. For medical conditions such as chronic back pain and fibromyalgia, it works to relieve pain.

What antidepressant works best with Cymbalta?

With respect to the combination group, the most commonly prescribed antidepressant with duloxetine was mirtazapine followed by paroxetine CR, escitalopram, venlafaxine, bupropion, sertraline and fluoxetine.