What is the classification of Spiriva Handihaler?


Long-acting anticholinergic.

What is Tiotropium classification?

Tiotropium belongs to the family of medicines known as bronchodilators. Bronchodilators are breathed in through the mouth to help open up the bronchial tubes (air passages) in the lungs. It is taken by inhalation (an inhaler) and will increase the flow of air to the lungs.

What type of bronchodilator is Spiriva?

Synopsis: Tiotropium (Spiriva) is a long-acting, anticholinergic bronchodilator for the long-term, once-daily, maintenance treatment of bronchospasm and dyspnea associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

What is Spiriva mechanism of action?

Tiotropium is a long-acting, specific muscarinic receptor antagonist or anticholinergic drug. Tiotropium inhibits the cholinergic (bronchoconstrictive) effects of acetylcholine by binding to the muscarinic receptors (M1–M5) in the bronchial smooth musculature (5).

What is the other Name for Spiriva?

Spiriva (tiotropium) is a good first-choice medication for controlling chronic obstructive pulmonary disease (COPD) and can also help control asthma.

What is generic Name for Spiriva?

Generic Name: tiotropium bromide

Tiotropium is used to control and prevent symptoms (such as wheezing, shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD which includes bronchitis and emphysema).

What is the mechanism of action of tiotropium?

Tiotropium works by blocking the muscarinic receptors for the neurotransmitter acetylcholine (Ach), which is released from cholinergic nerve endings in the airways. As tiotropium bromide is electrically charged, it is not absorbed by the gastrointestinal tract and does not pass the blood-brain barrier.

What are the contraindications of tiotropium?

Tiotropium bromide is contraindicated in patients with a hypersensitivity to tiotropium, ipratropium, and atropine (due to the risk of anaphylaxis) and narrow-angle glaucoma. Powder tiotropium capsules contain milk protein and are contraindicated for use in patients with allergies to milk.

What is the composition of ipratropium?

Ipratropium is a propanoate ester, a tropane alkaloid and a quaternary ammonium ion. Ipratropium is a quaternary ammonium derivative of [atropine] that acts as an anticholinergic agent.

What are the most common side effects of Spiriva?

The most common side effects reported with SPIRIVA HANDIHALER in patients with COPD include upper respiratory tract infection, dry mouth, sinus infection, sore throat, non-specific chest pain, urinary tract infection, indigestion, runny nose, constipation, increased heart rate, and blurred vision.

Who should not use Spiriva?

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How long should you take Spiriva?

When used as directed, SPIRIVA RESPIMAT helps to keep your airways open for a full 24 hours. It may take up to 4 to 8 weeks of treatment with SPIRIVA RESPIMAT for your breathing to improve.

What is the safest inhaler for COPD?

Advair. Advair is one of the most commonly used inhalers for the maintenance treatment of COPD. It is a combination of fluticasone, a corticosteroid, and salmeterol, a long-acting bronchodilator. Advair is used on a regular basis for the maintenance treatment of COPD and it is typically taken twice per day.

Does Spiriva affect sleep?

Insomnia, Hypersensitivity (including immediate reactions), and urticaria.

Does Spiriva improve lung function?

SPIRIVA RESPIMAT is a daily maintenance treatment that can help: Reduce your risk of COPD flare-ups. Improve lung function by opening airways. Control symptoms of COPD.

Does Spiriva raise blood pressure?

Very rarely, Spiriva has been related to increased blood pressure in people taking the drug for asthma treatment. In fact, in clinical studies of people with asthma, increased blood pressure occurred in 1% to 2% of people taking the drug.

How much does a 30 day supply of Spiriva cost?

The cost for Spiriva inhalation capsule 18 mcg is around $113 for a supply of 5 capsules, depending on the pharmacy you visit.

Inhalation Capsule.
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Does Spiriva dry up mucus?

Blocking these receptors stops the muscles in lungs from tightening (constricting). Spiriva also lowers mucus production. All these actions help to open your airways, making it easier to breathe.

Does Spiriva help shortness of breath?

It must be used regularly to prevent wheezing and shortness of breath. It works by relaxing the muscles around the airways so that they open up and you can breathe more easily.

Is Spiriva for asthma or COPD?

SPIRIVA RESPIMAT is intended as a once-daily maintenance treatment for COPD and asthma, and should not be used for the relief of acute symptoms, i.e., as rescue therapy for the treatment of acute episodes of bronchospasm.

Can you stop Spiriva suddenly?

Spiriva Respimat should only be used as the maintenance treatment of your COPD or asthma. Do not stop using your medicine or lower the dosage without checking with your doctor. If you stop using it suddenly or lower the dosage, the signs and symptoms of your COPD may worsen.