What are the major sympathomimetic drugs?

Sympathomimetic amines (epinephrine, norepinephrine, phenylephrine, dopamine, dobutamine, ephedrine, isoproterenol, metoproterenol, and isoetharine) are particularly susceptible to pharmacodynamic drug–drug interactions.

Which of these drugs is a sympathomimetic drug?

Sympathomimetics
DrugDrug Description
OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
PhenmetrazineUsed as an anorectic in the treatment of obesity.
DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.

Is caffeine a sympathomimetic drug?

Caffeine and paraxanthine have similar sympathomimetic actions. The activity of paraxanthine needs to be considered in understanding the clinical pharmacology of caffeine, particularly with chronic, repetitive caffeine consumption.

What are the most commonly abused sympathomimetics?

Some of the more commonly abused compounds include cocaine, the sympathomimetic amines (ie, amphetamine, methamphetamine), the “designer” hallucinogenic amphetamines (ie, 3,4-methylenedioxymetham- phetamine [MDMA], 3,4-methylenedioxyamphet- amine [MDA], 3,4-methylenedioxyethamphetamine [MDEA]), and methcathinone.

Is atropine a sympathomimetic drug?

Atropine can be used to prevent or abolish bradycardia or asystole induced by the injection of choline esters, anticholinesterase agents or other parasympathomimetic drugs, and cardiac arrest produced by stimulation of the vagus.

Are beta blockers sympathomimetic?

Certain β-blockers have an intrinsic sympathomimetic activity (partial agonist activity) at β1-adrenergic receptor sites, β2-adrenergic receptor sites, or both. In a β-blocker, this property is identified as a slight cardiac stimulation that can be blocked by propranolol.

What is meant by a sympathomimetic?

A sympathomimetic is any drug that causes an effect similar to that produced by stimulation of the sympathetic nervous system. Substances that mimic the effects of the sympathetic nervous system are called sympathomimetics.

What are sympathomimetics used to treat?

Sympathomimetic drugs form a classification of medication used to manage and treat cardiovascular pathology, hypersensitivity, COPD, and glaucoma.

Is salbutamol a sympathomimetic drug?

There are many sympathomimetic products available in treatment of asthma, such as ephedrin, isoproterenol, orciprenalin, salbutamol, terbutalin…, used by oral or injectable route and spray.

Which is an example of an adrenergic drug?

Examples of adrenergic drugs which selectively bind to alpha-1 receptors are phenylephrine and oxymetazoline. Selective alpha-2 receptor drugs include methyldopa and clonidine. The key beta-1 selective drug is dobutamine. Lastly, beta-2 selective drugs are bronchodilators, such as albuterol and salmeterol.

What are sympathomimetic agents used for?

Sympathomimetic drugs are used to treat cardiac arrest and low blood pressure, or even delay premature labor, among other things.

What is meant by a sympathomimetic?

A sympathomimetic is any drug that causes an effect similar to that produced by stimulation of the sympathetic nervous system. Substances that mimic the effects of the sympathetic nervous system are called sympathomimetics.

Is salbutamol a sympathomimetic drug?

There are many sympathomimetic products available in treatment of asthma, such as ephedrin, isoproterenol, orciprenalin, salbutamol, terbutalin…, used by oral or injectable route and spray.

Is epinephrine a sympathomimetic?

Epinephrine is a sympathomimetic catecholamine that exerts its pharmacologic effects on both alpha and beta-adrenergic receptors using a G protein-linked second messenger system.

When is sympathomimetic used?

Sympathomimetic drugs form a classification of medication used to manage and treat cardiovascular pathology, hypersensitivity, COPD, and glaucoma.

Are beta-2 agonists sympathomimetic?

Beta adrenergic agonists or beta agonists are medications that relax muscles of the airways, causing widening of the airways and resulting in easier breathing. They are a class of sympathomimetic agents, each acting upon the beta adrenoceptors.

Is propranolol a sympathomimetic?

Propranolol has an antifibrillatory action and it reduced the maximal rate at which the guinea-pig isolated atrium followed an electrical stimulus (Benfey & Varma, 1966). It appears that this action is greater in the presence of sympathomimetic drugs such as noradrenaline, adrenaline and phenylephrine.

Is adrenaline a bronchodilator?

Adrenaline may have beneficial effects in asthma in addition to a direct beta-adrenoceptor mediated bronchodilatation, such as alpha-receptor mediated reduction in microvascular leakage and oedema, and inhibition of bronchoconstrictor neural pathways.

What type of drug is adrenaline?

Adrenaline (Epinephrine) belongs to a class of drugs called sympathomimetic agents. Adrenaline injection can be used for the emergency treatment of severe allergic reactions.

What is another name for propranolol?

The extended-release propranolol capsule (brand name: Inderal LA) usually is taken once a day. The extended-release capsule (Innopran XL, Inderal XL) is usually taken at bedtime and should consistently be taken either always with or always without food each time.

What are examples of beta-blockers?

Examples of commonly used beta-blockers include:
  • atenolol (Tenormin)
  • bisoprolol (Cardicor, Emcor)
  • carvedilol.
  • metoprolol (Betaloc, Lopresor)
  • nebivolol (Nebilet)
  • propranolol (Inderal)

Why are they called beta-blockers?

Beta-blockers are beta receptor antagonists, meaning they block beta-adrenergic receptors and slow down certain types of cell activity.

What are the top 5 beta-blockers?

Which beta blocker is most effective?
  • Atenolol (Tenormin)
  • Betaxolol (Betoptic eye drops, Kerlone tablets)
  • Bisoprolol (Zebeta)
  • Esmolol (Brevibloc injection)
  • Metoprolol tartrate (Lopressor)
  • Metoprolol succinate (Toprol XL)
  • Nebivolol (Bystolic)