How would you describe basal cell carcinoma on a physical exam?


The hallmark of basal cell carcinoma is a waxy, translucent, or pearly appearance. Commonly, these lesions have central ulceration and a raised pale border (Figure 2). The border may be highlighted by applying traction on the skin around the lesion (Figure 3).

How do you identify basal cell carcinoma histology?

Usually, BCCs are well differentiated and cells appear histologically similar to basal cells of the epidermis. Tumor cells of nodular BCC, sometimes called basalioma cells, typically have large, hyperchromatic, oval nuclei and little cytoplasm. Cells appear uniform, and if present, mitotic figures are usually few.

What are the characteristics of squamous cell carcinoma?

What are the signs and symptoms of squamous cell carcinoma?
  • Rough, reddish scaly patch.
  • Open sore (often with a raised border)
  • Brown spot that looks like an age spot.
  • Firm, dome-shaped growth.
  • Wart-like growth.
  • Tiny, rhinoceros-shaped horn growing from your skin.
  • Sore developing in an old scar.

Is basal cell carcinoma flat or raised?

Basal cell carcinomas

These cancers can appear as: Flat, firm, pale or yellow areas, similar to a scar. Raised reddish patches that might be itchy. Small, pink or red, translucent, shiny, pearly bumps, which might have blue, brown, or black areas.

What can be mistaken for a basal cell carcinoma?

Trichoepithelioma is a benign tumor which can be easily confused with basal cell carcinoma. Since both tumors are histologically similar, it is important to distinguish them correctly as the courses for treatment are very different.

How can you tell the difference between BCC and SCC?

Squamous Cell Carcinoma

Though this form of skin cancer is not usually life-threatening, one major difference between basal cell and squamous cell cancers is that squamous cell cancer are more likely to grow deeper into the layers of your skin and spread to other parts of the body.

What does Morpheaform basal cell carcinoma look like?

Morpheaform Basal Cell Carcinoma (Sclerosing, Infiltrating)

It is called morpheaform or sclerosing due its clinical resemblance to an indurated plaque of morphea, or localized scleroderma. Lesions present as pink-to-ivory-white, shiny, smooth, scar-like, indurated plaques or depressions with ill-defined borders.

What is a Fibromyxoid stroma?

Stromal responses were recorded as present or absent and categorized as: fibromyxoid and/or inflammatory. As previously described, a fibromyxoid stromal response was defined as extracellular matrix composed of immature collagen and fibroblasts separating and surrounding the tumor cells (Figure 5).

Are basal cells Cuboidal?

Basal cells are cuboid in morphology and they are the germinative cells in the skin, and are constantly in the process of proliferating and differentiating into new cells that migrate toward the surface.

What is the difference between nodular and micronodular basal cell carcinoma?

Nodular BCC is the most common variant, characterized clinically by rolled edges, surface telangiectasia, and a central ulcer, giving rise to what is known as the rodent ulcer. The micronodular variant is an aggressive type of BCC that is liable to recurrence and difficult to eradicate.

What is an Evans tumor?

Low-grade fibromyxoid sarcoma, also known as Evans tumor, is a low-grade sarcoma that most commonly arises in the deep soft tissue of the proximal extremities or trunk in young adults. It is very rare in the viscera as a primary site, with only a few cases reported in the literature.

What is basal cell carcinoma nodular type?

Nodular basal cell carcinoma is the most common type of basal cell carcinoma and usually presents as a round, pearly, flesh-colored papule with telangiectases. More than 60% of BCCs belong to this subtype.

What is a myxoid tumor?

Myxoid/round cell liposarcoma, or MRCLS, is one of several types of liposarcoma. Liposarcoma is a rare cancer that grows in the cells that store fat in the body. MRCLS usually grows in the arms and legs. These tumors grow slowly, and they can spread to other parts of the body.

Are Cancerous tumors hard or soft?

Bumps that are cancerous are typically large, hard, painless to the touch and appear spontaneously. The mass will grow in size steadily over the weeks and months. Cancerous lumps that can be felt from the outside of your body can appear in the breast, testicle, or neck, but also in the arms and legs.

What does fibrosarcoma feel like?

persistent pain in the area of the tumor, which might feel like a sprain or “growing pains” swelling around the bone, which often does not show up until the tumor is quite large. difficulty moving a joint or limb. numbness in areas of the body, due to the tumor pressing on nerves.