What is the description of Klinefelter syndrome?

Klinefelter syndrome is a common genetic condition where a male is born with an extra X chromosome. Typically, a male has one X and one Y chromosome. People with Klinefelter syndrome can experience breast growth, breast cancer, osteoporosis, infertility and learning difficulties.

What are the characteristics of XYY syndrome?

taller than average height. low muscle tone, or muscle weakness (called hypotonia) very curved pinky finger (called clinodactyly) widely spaced eyes (called hypertelorism)

What type of abnormality is Klinefelter syndrome?

Klinefelter syndrome is a sex chromosome disorder in boys and men that results from the presence of an extra X chromosome in cells.

Can a girl have Klinefelter’s syndrome?

Klinefelter syndrome affects males only; females cannot have it. Klinefelter syndrome results from a genetic abnormality in which males have an extra copy of the X chromosome.

What gender is an XXY chromosome?

Usually, a female baby has 2 X chromosomes (XX) and a male has 1 X and 1 Y (XY). But in Klinefelter syndrome, a boy is born with an extra copy of the X chromosome (XXY). The X chromosome is not a “female” chromosome and is present in everyone.

What is an XXY baby?

Boys who have Klinefelter syndrome are born with it. It’s also called XXY because they have an extra X chromosome in most or all their cells. Usually, a person has 46 chromosomes in each cell, divided into 23 pairs, which includes two sex chromosomes.

Why is Klinefelter so tall?

From early school age, boys with Klinefelter syndrome tend to be taller (increased leg length) in part because testosterone (via conversion to oestrogen) normally stops the long bones from growing after puberty. This increase in height is maintained throughout life.

Who is most at risk for Klinefelter?

This is written as XXY. Klinefelter syndrome occurs in about 1 out of 500 to 1,000 baby boys. Women who get pregnant after age 35 are slightly more likely to have a boy with this syndrome than younger women.

Is Klinefelter an intersex?

(IFAS 2000, p. 2). Therefore, according to the NZKA, not all XXY individuals will develop Klinefelter Syndrome, for the Syndrome is simply a form of male hypogonadism, caused by a lack of testosterone: thus XXY is not an intersex condition.

What is XYY syndrome called?

Males with XYY syndrome have 47 chromosomes because of the extra Y chromosome. This condition is also sometimes called Jacob’s syndrome, XYY karyotype, or YY syndrome. According to the National Institutes of Health, XYY syndrome occurs in 1 out of every 1,000 boys.

What type of mutation is XYY syndrome?

XYY syndrome is a rare chromosomal disorder that affects males. It is caused by the presence of an extra Y chromosome. Males normally have one X and one Y chromosome. However, individuals with this syndrome have one X and two Y chromosomes.

How is XYY syndrome diagnosed?

47, XYY syndrome is caused by having an extra copy of the Y chromosome in every cell of the body. The syndrome is usually not inherited. Diagnosis can be made based on prenatal tests, or it may occur during childhood or adulthood if a male has signs or symptoms of the disease.

Is XYY syndrome the same as Down syndrome?

The XYY occurs when 24YY spermatozoa are formed due to non-disjunction either at paternal meiosis II or mitosis. Unlike Down syndrome, the XYY is not associated with increased parental age.

CAN XXY have babies?

It is possible that an XXY male could get a woman pregnant naturally. Although sperm are found in more than 50% of men with KS3, low sperm production could make conception very difficult.

Is Klinefelter syndrome dominant or recessive?

Klinefelter syndrome with fabry disease–a case of nondisjunction of the X-chromosome with sex-linked recessive mutation. Heart Lung Circ. 2014 Dec;23(12):1149-52.

Can females have Jacobs syndrome?

Being male is the biggest risk factor. Most cases of XYY syndrome are not inherited, and the syndrome occurs randomly in pregnancies of women from all ages and ethnic backgrounds.

Is Klinefelter an intersex?

(IFAS 2000, p. 2). Therefore, according to the NZKA, not all XXY individuals will develop Klinefelter Syndrome, for the Syndrome is simply a form of male hypogonadism, caused by a lack of testosterone: thus XXY is not an intersex condition.

Why are Klinefelter males tall?

From early school age, boys with Klinefelter syndrome tend to be taller (increased leg length) in part because testosterone (via conversion to oestrogen) normally stops the long bones from growing after puberty. This increase in height is maintained throughout life.