What is the classification of captopril?

Captopril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It decreases certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently.

What medications are ACE inhibitors?

Angiotensin-converting enzyme inhibitor (ACE inhibitors) drugs include Benazepril (Lotensin), Captopril (Capoten), Enalapril/Enalaprilat (Vasotec oral and injectable), Fosinopril (Monopril), Lisinopril (Zestril and Prinivil), Moexipril (Univasc), Perindopril (Aceon), Quinapril (Accupril), Ramipril (Altace), and …

How many ACE inhibitors are there?

How many ACE inhibitors are there? There are 10 different ACE inhibitors (as of Aug. 2021) approved by the FDA.

What are the common indications for ACE inhibitors?

  • Hypertension. …
  • Heart Failure. …
  • Post Myocardial Infarction. …
  • Diabetes. …
  • Nephrotic Syndrome or Proteinuria. …
  • Chronic Kidney Disease. …
  • Glomerular Disease and Post-transplant Glomerulonephritis\

Which is the best ACE inhibitor?

The best ACE inhibitors for hypertension include Trandolapril, Enalapril, and Ramipril. Angiotensin-converting enzyme (ACE) inhibitors are a group of medications indicated for the treatment of hypertension (high blood pressure).

What is difference between ACE inhibitor and beta blocker?

They are both used for conditions like high blood pressure and heart failure. ACE inhibitors mainly lower blood pressure by relaxing blood vessels in the body. Beta blockers mainly lower the heart rate, but they can also relax blood vessels.

What are the contraindications of ACE inhibitors?

Absolute Contraindications

Any patient with a history of angioneurotic edema, whether related to an ACE inhibitor, angiotensin receptor blockers, or another cause, should not be given an ACE inhibitor. Other contraindications include pregnancy, renal artery stenosis, and previous allergy to ACE inhibitors.

What is the mechanism of ACE inhibitors?

Mechanism of action. ACE inhibitors reduce the activity of the renin–angiotensin–aldosterone system (RAAS) as the primary etiologic (causal) event in the development of hypertension in people with diabetes mellitus, as part of the insulin-resistance syndrome or as a manifestation of renal disease.

What are ACE inhibitors contraindicated in?

Contraindications to ACEI use include hyperkalemia (>5.5 mmol/L), renal artery stenosis, pregnancy (ACEI or Australian Drug Evaluation Committee [ADEC] pregnancy category D), or prior adverse reaction to an ACEI including angioedema.

What is the best and safest blood pressure medication?

the ACE inhibitor lisinopril (Prinivil, Zestril) tops the list, followed by amlodipine besylate (Norvasc), a calcium channel blocker, and. generic hydrochlorothiazide (HCTZ).

Is amlodipine an ACE inhibitors?

Amlodipine relaxes (widens) blood vessels and improves blood flow. Benazepril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Similar Drugs.
Generic ExamplesSupplied AsStrength
Amlodipine Besylate-Benazepril HydrochlorideCapsule5 Mg-10 Mg5 Mg-20 Mg2.5Mg-10Mg10 Mg-40Mg5 Mg-40 Mg10 Mg-20Mg

What medications should not be taken with ACE inhibitors?

Over-the-counter medicines can affect ACE inhibitors. You should not take ibuprofen (brand name: Advil) or naproxen sodium (brand name: Aleve). These medicines make ACE inhibitors less effective.

What should be avoided when taking ACE inhibitors?

So, people taking ACE inhibitors should avoid eating large amounts of foods high in potassium, such as bananas. Other foods high in potassium include avocados, beets, oranges and orange juice, potatoes, spinach, tomatoes and tomato sauce, as well as salt substitutes. Vitamin K is essential for proper blood-clotting.

What is the first choice drug for hypertension?

We concluded in 2004 that the first-choice treatment for hypertension in adults was single-agent therapy with the thiazide diuretic chlortalidone or, when this drug is not available, the thiazide diuretic hydrochlorothiazide.

Which ARB is best for hypertension?

To sum it up: Olmesartan and telmisartan are equally effective at reducing blood pressure, whereas losartan is less effective. Telmisartan is best in terms of cholesterol-lowering effects. And among the three, only telmisartan has a blood sugar-lowering effect.

Which is safer amlodipine or lisinopril?

However, the patients randomly assigned to lisinopril experienced higher risks of stroke, combined cardiovascular disease, gastrointestinal bleeding, and angioedema, whereas the risk of heart failure was higher in the amlodipine group.

What is the second-line treatment for hypertension?

Among the 26 998 patients who were initially treated with a single ARB (from one database), calcium channel blockers (CCBs) were the most frequently prescribed second-line antihypertensive, as these medicines were added for >20% of patients within 1 year of ARB prescription initiation.

What is the best diuretic for high blood pressure?

Thiazide diuretics are recommended as one of the first drug treatments for high blood pressure.