What is alendronate used for?

Alendronate is used to prevent and treat osteoporosis (thinning of the bone) in women after menopause. This medicine may also be used to increase bone mass in men who have osteoporosis, and in men and women to prevent and treat osteoporosis caused by long-term use of corticosteroids (cortisone-like medicine).

What is another name for alendronate?

Alendronate is commonly known by the brand name Fosamax®. Fosamax® is a bisphosphonate and is used in the treatment of osteoporosis. Fosamax® decreases the rate bone cells are absorbed. This reduced absorption allows the body to increase bone density, which in turn reduces the risk of fracture.

What drug class is used for osteoporosis?

Antiresorptive medications include a class of drugs called bisphosphonates. These medications include: Alendronate (Fosamaxâ„¢, Fosamaxâ„¢ Plus D) Risedronate (Actonelâ„¢, Actonelâ„¢ with Calcium, and Atelviaâ„¢)

What is the mode of action of alendronate?

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro – PMC.

What are side effects of alendronate?

This medication may rarely cause serious irritation and ulcers of the esophagus. If you notice any of the following unlikely but very serious side effects, stop taking alendronate and talk to your doctor or pharmacist right away: new or worsening heartburn, chest pain, pain or difficulty when swallowing.

What drugs are bisphosphonates?

Bisphosponates such as risedronate (Actonel), alendronate (Fosamax), ibandronate (Boniva), zoledronic acid (Reclast), and pamidronate (Aredia) are used to treat and prevent osteoporosis—or, bone thinning—which occurs when the bones lose calcium and other minerals that help keep them strong and compact.

What is the safest drug for osteoporosis?

Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill.

What foods destroy bone density?

What foods destroy bone density?
  • Excess salt.
  • Hydrogenated oil.
  • Alcohol.
  • Food rich in vitamin A.
  • Soft drinks.

Can you take vitamin D with alendronate?

It will also help prevent irritation to your esophagus. It is important that you eat a well-balanced diet with adequate amounts of calcium and vitamin D (found in milk or other dairy products). However, do not take any foods, beverages, or calcium supplements within 30 minutes or longer after taking this medicine.

What exercises should be avoided with osteoporosis?

If you have osteoporosis, don’t do the following types of exercises: High-impact exercises. Activities such as jumping, running or jogging can lead to fractures in weakened bones. Avoid jerky, rapid movements in general.

Why is spinach not good for osteoporosis?

Spinach and Other Foods with Oxalates

Your body doesn’t absorb calcium well from foods that are high in oxalates (oxalic acid) such as spinach. Other foods with oxalates are rhubarb, beet greens and certain beans. These foods contain other healthy nutrients, but they just shouldn’t be counted as sources of calcium.

Does chocolate affect bone density?

Chocolate is a rich source of antioxidant and antiinflammatory flavonoids and dietary minerals with the potential to benefit bone health. However, other chocolate constituents such as cocoa butter, sugar, and methylxanthines may be detrimental to bone.

Does walking increase bone density?

Weight-bearing exercises, such as walking, jogging, and climbing stairs, can help you build strong bones and slow bone loss.

What organs are affected by osteoporosis?

Osteoporosis causes bones to become weak and brittle — so brittle that a fall or even mild stresses such as bending over or coughing can cause a fracture. Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. Bone is living tissue that is constantly being broken down and replaced.

What is the newest treatment for osteoporosis?

Romosozumab (Evenity).

This is the newest bone-building medication to treat osteoporosis. It is given as an injection every month at your doctor’s office and is limited to one year of treatment.

Which fruit is best for bones?

Citrus fruits have vitamin C, which has been shown to help prevent bone loss. One whole pink or red grapefruit has about 88 milligrams of vitamin C, giving you the amount you need for the entire day.

What type of exercise increases bone density?

Weight-bearing and resistance exercises are the best for your bones. Weight-bearing exercises force you to work against gravity. They include walking, hiking, jogging, climbing stairs, playing tennis, and dancing. Resistance exercises – such as lifting weights – can also strengthen bones.