Classification of atorvastatin
What are statins classification?
Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease. They are the most common cholesterol-lowering drugs.
What is the indication for atorvastatin?
Atorvastatin is indicated for the treatment of several types of dyslipidemias, including primary hyperlipidemia and mixed dyslipidemia in adults, hypertriglyceridemia, primary dysbetalipoproteinemia, homozygous familial hypercholesterolemia, and heterozygous familial hypercholesterolemia in adolescent patients with …
Is atorvastatin a Antihyperlipidemic?
We evaluated the effects of 3 antihyperlipidemic drugs (pravastatin, atorvastatin, and fenofibrate), which have different mechanisms of action and different patterns of action on lipid profiles, on erythrocyte deformability and fibrinogen levels in patients with type IIa and type IIb hyperlipidemia.
What is atorvastatin mechanism of action?
Mechanism of Action
Atorvastatin is a selective, competitive inhibitor of HMG-CoA reductase, the rate- limiting enzyme that converts 3-hydroxy-3-methylglutaryl-coenzyme A to mevalonate, a precursor of sterols, including cholesterol.
What are atorvastatin side effects?
Common side effects
- Feeling sick (nausea) or indigestion. Stick to simple meals and do not eat rich or spicy food. …
- Headaches. Make sure you rest and drink plenty of fluids. …
- Nosebleeds. …
- Sore throat. …
- Cold-like symptoms, such as a runny nose, blocked nose or sneezing. …
- Constipation or farting (flatulence) …
- Diarrhoea.
What are the benefits of atorvastatin?
Cholesterol-lowering statins such as Lipitor (atorvastatin) and Crestor (rosuvastatin calcium) are among the most widely prescribed drugs on the market today. Their purpose is to lower blood cholesterol by reducing the amount of cholesterol produced by the liver, but they have several other effects.
What is another name for atorvastatin?
Atorvastatin (Lipitor) helps improve your cholesterol levels and is a common first-choice medication for people with high cholesterol or heart disease. It is also used for people who are at higher risk of heart disease, such as those with diabetes, even though they may have normal cholesterol levels.
Is atorvastatin a anticoagulant?
Nonetheless, it is important to recognize that despite its various actions, atorvastatin should not be considered an anticoagulant or blood thinner. The term “blood thinner” implies an extensive reduction in clotting, as well as an increase in bleeding risk as a consequence.
Is atorvastatin an antihypertensive?
Low-dose atorvastatin reduces ambulatory blood pressure in patients with mild hypertension and hypercholesterolaemia: a double-blind, randomized, placebo-controlled study.
What foods should be avoided when taking atorvastatin?
A: While taking atorvastatin (Lipitor), avoid high-fat and high-cholesterol foods as part of your overall treatment. You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of serious side effects. Also, avoid excess alcohol use, as this may cause serious liver problems.
Is atorvastatin used for blood pressure?
Low-dose atorvastatin reduces ambulatory blood pressure in patients with mild hypertension and hypercholesterolaemia: a double-blind, randomized, placebo-controlled study.
What is atorvastatin 20 mg tablet used for?
Atorvastatin is used along with a proper diet to help lower “bad” cholesterol and fats (such as LDL, triglycerides) and raise “good” cholesterol (HDL) in the blood. It belongs to a group of drugs known as “statins.” It works by reducing the amount of cholesterol made by the liver.
What drugs should not be taken with atorvastatin?
Certain drugs can interact with atorvastatin (Lipitor) and increase its side effects. These include fibrates, niacin supplements, cyclosporine, clarithromycin, itraconazole, HIV protease inhibitors, oral contraceptives containing norethindrone or ethinyl estradiol, digoxin, rifampin, and colchicine.
Does atorvastatin affect memory?
Neurological side effects
The FDA warns on statin labels that some people have developed memory loss or confusion while taking statins. These side effects reverse once you stop taking the medication.
What is the most common side effect of statins?
Myalgia is the most common side effect of statin use, with documented rates from 1-10%. Rhabdomyolysis is the most serious adverse effect from statin use, though it occurs quite rarely (less than 0.1%). The most common risk factors for statin-related myopathy include hypothyroidism, polypharmacy and alcohol abuse.