What is the classification of atropine?

Atropine is commonly classified as an anticholinergic or antiparasympathetic (parasympatholytic) drug. More precisely, however, it is termed an antimuscarinic agent since it antagonizes the muscarine-like actions of acetylcholine and other choline esters.

What is the intended action of atropine sulfate?

Atropine Sulfate Injection, USP, is indicated for temporary blockade of severe or life threatening muscarinic effects, e.g., as an antisialagogue, an antivagal agent, an antidote for organophosphorus or muscarinic mushroom poisoning, and to treat bradyasystolic cardiac arrest.

Is atropine sulfate an anticholinergic?

Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4 and M5. It is classified as an anticholinergic drug (parasympatholytic).

What is another name for atropine sulfate?

BRAND NAME(S): Isopto Atropine. USES: This medication is used before eye examinations (e.g., refraction) and to treat certain eye conditions (e.g., uveitis).

What is atropine is used for?

Ophthalmic atropine is used before eye examinations to dilate (open) the pupil, the black part of the eye through which you see. It is also used to relieve pain caused by swelling and inflammation of the eye.

What are the indications of atropine?

The intramuscular use of atropine in the form of a pen injector is indicated for the treatment of poisoning by susceptible organophosphorus nerve agents having cholinesterase activity as well as organophosphorus or carbamate insecticides in adult and pediatric patients.

What is the action of inj atropine?

Atropine Injection is given before anaesthesia to decrease mucus secretions, such as saliva. During anaesthesia and surgery, atropine is used to help keep the heart beat normal. Atropine sulfate monohydrate is also used to block or reverse the adverse effects caused by some medicines and certain type of pesticides.

What is the desired effect of atropine sulfate when used as a preoperative medication?

Atropine may be used during pregnancy as a preoperative, preanesthetic agent to reduce salivation and bronchial secretions. Atropine rapidly crosses the human placenta.

How does atropine sulfate achieve its desired therapeutic effect?

Mechanism of action. The most important therapeutic action of atropine is the inhibition of smooth muscle and glands innervated by postganglionic cholinergic nerves. It also has central nervous system activity, which may be stimulating or depressing depending upon the dose.

What is atropine used for in an emergency?

It is used in emergency situations when the heart beats too slowly, as an antidote to for example organophosphate insecticide or nerve gas poisoning and in mushroom poisoning. It can be used as part of the premedication before general anaesthesia.

What are the contraindications of atropine?

Atropine generally is contraindicated in patients with glaucoma, pyloric stenosis, thyrotoxicosis, fever, urinary tract obstruction and ileus.

What is a common side effect of atropine?

These include dryness of the mouth, blurred vision, dry eyes, photophobia, confusion, headache, dizziness, fatigue, tachycardia, palpitations, flushing, urinary hesitance or retention, constipation, abdominal pain, abdominal distention, nausea, vomiting, loss of libido, and impotency.

What are the advantages of giving atropine sulfate before surgery and why?

Atropine Injection is given before anaesthesia to decrease mucus secretions, such as saliva. During anaesthesia and surgery, atropine is used to help keep the heart beat normal. Atropine sulfate monohydrate is also used to block or reverse the adverse effects caused by some medicines and certain type of pesticides.

What is patient teaching for atropine?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid becoming overheated or dehydrated during exercise and in hot weather. Atropine can decrease sweating and you may be more prone to heat stroke.

Does atropine affect blood pressure?

Most cases occurred shortly after atropine, i.e. before anaesthesia. Heart rate increased significantly in both groups, more so after atropine (up to 60%), and remained elevated. In both groups blood pressure fell after the induction of anaesthesia but was close to control during surgery.

What are the nursing responsibility for atropine?

Avoid driving or operating heavy machinery while under the influence of atropine. Reduce lighting to decrease photophobia. Monitor GI motility (BMs and flatus) and urine output while patient is receiving atropine. Atropine is a common pre-operative agent, and can be given IM, SC, PO, or IV.

Does atropine cause blurred vision?

Atropine will cause blurred vision which may last for some time. Make sure you can see clearly again before you drive and before you use tools or machines.

Can nurses give atropine?

An certified critical care nurse may administer a dose of Atropine 0.5 mg IV or Intraosseus (IO) direct by Medical Directive. The nurse may repeat with a second dose of 1 mg.

When does atropine stop?

#1.

Atropine works by poisoning the vagus nerve, thereby removing parasympathetic inputs to the heart. This works beautifully for vagally-mediated bradycardia (e.g. vagal reflexes, cholinergic drugs). However, it fails for bradycardias caused by other mechanisms (e.g. heart block beyond the AV node).

Which medication is given as an antidote for an overdose of atropine?

Physostigmine, given as an atropine antidote by slow intravenous injection of 1 to 4 mg (0.5 to 1 mg in pediatric populations), rapidly abolishes delirium and coma caused by large doses of atropine.