Classification of calcitriol
What is the action of calcitriol?
Calcitriol acts on cells in the gastrointestinal tract to increase the production of calcium transport proteins, termed calbindin-D proteins, which results in increased uptake of calcium from the gut into the body. This is the only mechanism by which the body can increase its calcium stores.
What is the classification of cholecalciferol?
Cholecalciferol (vitamin D3) is in a class of medications called vitamin D analogs.
What is the common name for calcitriol?
Rocaltrol (calcitriol) is a synthetic version of Vitamin D3 used to treat calcium deficiency with hypoparathyroidism (decreased functioning of the parathyroid glands) and metabolic bone disease in people with chronic kidney failure.
Why calcitriol is called hormone?
Calcitriol is the active form of vitamin D, normally made in the kidney. It is also known as 1,25-dihydroxycholecalciferol. It is a hormone which binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes.
What is vitamin D classified as in chemistry?
Chemically, the various forms of vitamin D are secosteroids, that is, steroids in which one of the bonds in the steroid rings is broken.
What is the difference between calcitriol and cholecalciferol?
The main difference between cholecalciferol and calcitriol is that cholecalciferol is a type of vitamin D that is made by the skin when exposed to sunlight whereas calcitriol is the active form of vitamin D that occurs in the kidney. Cholecalciferol and calcitriol are two forms of vitamin D with different functions.
Is calcitriol a steroid hormone?
The endogenous serum metabolite of vitamin D (calcitriol, 1,25(OH)2 D3 ) is considered a true steroid hormone (D hormone), and like glucocorticoids (GCs) and gonadal hormones, may exert several immunomodulatory activities.
What is the meaning of calcitriol?
(KAL-sih-TRY-ol) The active form of vitamin D. Calcitriol is formed in the kidneys or made in the laboratory. It is used as a drug to increase calcium levels in the body in order to treat skeletal and tissue-related calcium deficiencies caused by kidney or thyroid disorders.
What vitamins are in calcitriol?
The liver and kidneys convert vitamin D (produced in the skin and taken up in the diet), into the active hormone, which is called calcitriol. Active vitamin D helps to increase the amount of calcium the gut can absorb from eaten food into the bloodstream and also prevents calcium loss from the kidneys.
What drug classification is cyanocobalamin?
Cyanocobalamin may be used alone or with other medications. Cyanocobalamin belongs to a class of drugs called B Vitamins; Vitamins, Water-Soluble.
What is cholecalciferol used for?
Descriptions. Cholecalciferol is a dietary supplement that is used to treat vitamin D deficiency. It is also used with calcium to maintain bone strength. This medicine is available both over-the-counter (OTC) and with your doctor’s prescription.
Is cholecalciferol a steroid?
Cholecalciferol is one of the five forms of vitamin D. Cholecalciferol is a secosteroid, that is, a steroid molecule with one ring open.
What are the indications of cholecalciferol?
Cholecalciferol use is indicated for the treatment of specific medical conditions like refractory rickets (or vitamin D resistant rickets), hypoparathyroidism, and familial hypophosphatemia 12,13.
What is the difference between vitamin D and cholecalciferol?
Vitamin D, also known as cholecalciferol, is a vitamin that your body needs to absorb calcium. Vitamin D is made in the skin when it is exposed to sunlight. It can also be found in some foods like fatty fish and eggs. Your body needs vitamin D to maintain strong bones and muscles.
What is the difference between vitamin D and vitamin D3?
There are quite a few differences between vitamin D and vitamin D3 but the main difference between them is that vitamin D is a fat-soluble vitamin that regulates calcium and phosphorous levels of the body whereas the vitamin D3 is the natural form of vitamin D produced by the body from sunlight.