Classification of cholecalciferol
What is the mechanism of action for cholecalciferol?
The activated form of cholecalciferol binds to vitamin D receptors and modulates gene expression. This leads to an increase in serum calcium concentrations by increasing intestinal absorption of phosphorus and calcium, promoting distal renal tubular reabsorption of calcium and increasing osteoclastic resorption.
What is colecalciferol also known as?
Colecalciferol is also know as vitamin D3. Type of medicine. Also called. Vitamin D supplement.
What is the composition of cholecalciferol?
Types
| Name | Chemical composition |
|---|---|
| Vitamin D1 | Mixture of molecular compounds of ergocalciferol with lumisterol, 1:1 |
| Vitamin D2 | ergocalciferol (made from ergosterol) |
| Vitamin D3 | cholecalciferol (made from 7-dehydrocholesterol in the skin). |
| Vitamin D4 | 22-dihydroergocalciferol |
What are the indications of cholecalciferol?
Cholecalciferol use is indicated for the treatment of specific medical conditions like refractory rickets (or vitamin D resistant rickets), hypoparathyroidism, and familial hypophosphatemia 12,13.
What is the drug colecalciferol used for?
Colecalciferol is a form of vitamin D used in the prevention and treatment of vitamin D deficiency conditions. It may also be prescribed for certain bone conditions, such as thinning of the bone (osteoporosis) when it will be given to you with other medicines.
What is the difference between vitamin D and cholecalciferol?
Vitamin D, also known as cholecalciferol, is a vitamin that your body needs to absorb calcium. Vitamin D is made in the skin when it is exposed to sunlight. It can also be found in some foods like fatty fish and eggs. Your body needs vitamin D to maintain strong bones and muscles.
What is cholecalciferol side effects?
Cholecalciferol side effects
chest pain, feeling short of breath; growth problems (in a child taking cholecalciferol); or. early signs of vitamin D overdose–weakness, metallic taste in your mouth, weight loss, muscle or bone pain, constipation, nausea, and vomiting.
What is the half life of cholecalciferol?
RECENT estimates1,2, based on observations of radio-isotopically labelled cholecalciferol for up to 4 days, suggest that the biological half-life of vitamin D in human plasma does not exceed 50 h.
When should cholecalciferol be taken?
It should be taken as soon as you get out of bed in the morning and at least 30 minutes before any food, beverage, or other medicines. Food and beverages (eg, mineral water, coffee, tea, or juice) will decrease the amount of alendronate and cholecalciferol combination absorbed by the body.
Is cholecalciferol the same as vitamin D3?
Vitamin D3 is cholecalciferol and comes from animal-based sources. Both supplements are processed in the body by the liver to 25-hydroxyvitamin D, though vitamin D3 is thought to provide higher levels of 25D.
Is cholecalciferol a vitamin D3?
Cholecalciferol (Vitamin D3)
What are the side effects of taking colecalciferol?
Cholecalciferol side effects
chest pain, feeling short of breath; growth problems (in a child taking cholecalciferol); or. early signs of vitamin D overdose–weakness, metallic taste in your mouth, weight loss, muscle or bone pain, constipation, nausea, and vomiting.
Is Adcal D3 the same as colecalciferol?
What is Adcal D3 and how does it work? Adcal D3 is a brand of medicine which contains the ingredients calcium and colecalciferol (otherwise known as vitamin D3) and is taken as a supplement by children and adults, over 12 years old, to help support strong bones and teeth in adults.
Is cholecalciferol an active form of vitamin D?
Cholecalciferol, also known as vitamin D3 and colecalciferol, is a type of vitamin D that is made by the skin when exposed to sunlight; it is found in some foods and can be taken as a dietary supplement.
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Cholecalciferol.
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Cholecalciferol.
| Clinical data | |
|---|---|
| Melting point | 83 to 86 °C (181 to 187 °F) |
| Boiling point | 496.4 °C (925.5 °F) |
What is the chemical name of vitamin D3?
What is vitamin D3 derived from?
Few foods are naturally rich in vitamin D3. The best sources are the flesh of fatty fish and fish liver oils. Smaller amounts are found in egg yolks, cheese, and beef liver.
What is vitamin D classified as in chemistry?
Chemistry. Vitamin D is a generic term and indicates a molecule with a steroidal structure that has four rings of A, B, C, and D with differing side chain structures (FIGURE 1). The A, B, C, and D ring structure is derived from the parent compound cholesterol. Technically, vitamin D is classified as a secosteroid.
Is cholecalciferol a vitamin D analogues?
The preferred vitamin D analog for daily supplementation is cholecalciferol (vitamin D3). The active form of vitamin D3 is 1,25-dihydroxy-vitamin D3. Alfacalcidol, calcitriol and eldecalcitol are used to treat osteoporosis in Japan.
What is the half life of cholecalciferol?
RECENT estimates1,2, based on observations of radio-isotopically labelled cholecalciferol for up to 4 days, suggest that the biological half-life of vitamin D in human plasma does not exceed 50 h.
Why is vitamin D called a vitamin?
Vitamin D is actually a hormone rather than a vitamin; it is required to absorb calcium from the gut into the bloodstream. Vitamin D is mostly produced in the skin in response to sunlight and is also absorbed from food eaten (about 10% of vitamin D is absorbed this way) as part of a healthy balanced diet.
Is vitamin D a protein?
The vitamin D binding protein (DBP) is a multifunctional protein that is well-conserved in the evolution of vertebrates. We review the history of the discovery of this gene and protein and summarize its main functions as known today.