What type of anticoagulant is Pradaxa?

PRADAXA is a type of anticoagulant (blood thinner) known as a direct thrombin inhibitor. It is used to lower the chance of blood clots forming in your body by blocking thrombin—the blood’s central clotting agent. See how PRADAXA works for: AFib.

Is Pradaxa an anticoagulant or antiplatelet?

This is because PRADAXA is a blood-thinning medicine (anticoagulant) that lowers the chance of blood clots forming in your body.

What is Pradaxa mechanism of action?

Mechanism of Action

Dabigatran (Pradaxa) reversibly binds to the active site on the thrombin molecule, preventing thrombin-mediated activation of coagulation factors. It may have less of an antagonistic effect on thrombin-mediated platelet aggregation (see “Adverse Effects” section).

What is the classification of rivaroxaban?

Rivaroxaban is in a class of medications called factor Xa inhibitors. It works by blocking the action of a certain natural substance that helps blood clots to form.

What are the four classes of anticoagulants?

Anticoagulants may be divided into four main groups: coumarins and indandiones; factor Xa inhibitors; heparins; and direct thrombin inhibitors.

What is difference between antiplatelet and anticoagulant?

There are different types of blood thinners: Anticoagulants, such as heparin or warfarin (also called Coumadin), slow down your body’s process of making clots. Antiplatelets, such as aspirin and clopidogrel, prevent blood cells called platelets from clumping together to form a clot.

What class of drug is warfarin?

Warfarin is in a class of medications called anticoagulants (‘blood thinners’). It works by decreasing the clotting ability of the blood.

What is the generic name and indication for Pradaxa?

Pradaxa (dabigatran) is an anticoagulant that works by blocking the clotting protein thrombin. Pradaxa is used to prevent blood clots from forming because of a certain irregular heart rhythm (atrial fibrillation). Preventing these blood clots helps to reduce the risk of a stroke.

What class of drug is clopidogrel?

Clopidogrel is in a class of medications called antiplatelet medications. It works by preventing platelets (a type of blood cell) from collecting and forming clots that may cause a heart attack or stroke.

What is the most common side effects of Pradaxa?

Side Effects
  • Acid or sour stomach.
  • belching.
  • black, tarry stools.
  • bloody stools.
  • pain or burning in the throat.
  • stomach discomfort, upset, burning, or pain.
  • vomiting of blood or material that looks like coffee grounds.

What foods should you avoid when taking Pradaxa?

Are There Foods to Avoid While Taking Pradaxa? Patients taking older anticoagulants, such as warfarin, were required to avoid eating foods that were high in vitamin K, such as cabbage, spring onions, broccoli, fermented soy products, Brussels sprouts, and kale and other leafy greens.

What are the top 5 anticoagulant drugs?

The most commonly prescribed anticoagulant is warfarin.
…
Types of anticoagulants
  • rivaroxaban (Xarelto)
  • dabigatran (Pradaxa)
  • apixaban (Eliquis)
  • edoxaban (Lixiana)

How long can you stay on Pradaxa?

Treatment with Pradaxa should be started within 1 – 4 hours of completed surgery, using a single capsule of 110 mg and continuing with 2 capsules of 110 mg once daily for a total of 10 days (after knee replacement surgery) or for a total of 28 – 35 days (after hip replacement surgery).

Does Pradaxa cause tiredness?

It’s important to watch for symptoms of bleeding while you’re taking Pradaxa. Tell your doctor if you have any of the following: fatigue (lack of energy)

When is the best time to take Pradaxa?

Take PRADAXA Capsules twice a day (approximately every 12 hours) If you miss a dose of PRADAXA Capsules, take it as soon as you remember. If your next dose is less than 6 hours away, skip the missed dose. Do not take two doses of PRADAXA Capsules at the same time.

Are there food restrictions with Pradaxa?

3. Does PRADAXA have any dietary restrictions? Unlike warfarin, PRADAXA has no dietary restrictions, so taking PRADAXA requires no change to your diet.

Does Pradaxa cause liver damage?

A review of the scientific literature did not find any published studies that showed an increased risk of liver injury in patients treated with Pradaxa. Product labels in the United States and the European Union do not contain any information specific to liver injury.

Can Pradaxa cause hair loss?

Hair loss is not a known side effect of the NOACs rivaroxaban, dabigatran or apixaban.

What fruits should you avoid if you are on blood thinners?

Grapefruit and other citrus fruits can interfere with how your body metabolizes these medications.

Does Pradaxa cause joint pain?

Like all blood thinners, Pradaxa can also cause significant and sometimes fatal bleeds. The drug also interacts with other medications, including common painkillers, in ways that can increase this risk. Signs and symptoms of serious bleeding can include: Joint pain, swelling or discomfort joint.