What is tetracycline discoloration?

The tetracycline will oxidize once the teeth have had exposure to light. Then the discoloration will change from fluorescent yellow to nonfluorescent brown or grey. This discoloration process happens over a period of a few months to years.

When does tetracycline staining occur?

Tetracyclines lead to permanent tooth staining when ingested during pregnancy, nursing, or during the developmental period of secondary and primary teeth. This vulnerable time frame is from the fourth month in utero through the fifth month of postpartum. The overall prevalence of tetracycline staining is 3% to 4%.

Does tetracycline stain dentin or enamel?

Tetracycline is known to cause permanent discolouration during odontogenesis in children by the formation of insoluble tetracycline–calcium orthophosphate complexes in the dentine and enamel which darken upon exposure to light.

Why do antibiotics stain teeth?

Tetracycline stains teeth because it can bond to calcium ions as teeth are developing. Since calcium ions acquire during this development, the stain becomes inherently part of the tooth’s structure.

Why do tetracyclines cause photosensitivity?

Two major types of damage induced in DNA molecules by the photosensitizing activity of tetracycline derivatives are proposed; these are alteration of guanine residues and breakage of the sugar-phosphate backbone.

How does tetracycline whiten teeth discolored?


Since tetracycline stains tend to be dark and deep within the tooth, you will likely need a high concentration of bleaching agent to produce results. If you have tetracycline stains, in-office teeth whitening with a high concentration of peroxide can significantly lighten your teeth.

Can tetracycline stains be removed?

Tetracycline stains are much more difficult.

The simple fact is that tetracycline color molecules cannot be completely removed from teeth. Thus, the amount of whitening that can be achieved when using typical whitening systems is limited.

Why is my tooth turning GREY?

According to the American Dental Association, if a tooth is damaged due to trauma or infection, the pulp and nerves can die and the tooth turns dark, pink, gray or black. Metal: Some materials used in the past by dentists to repair teeth such as silver fillings may also lead to graying of teeth over time.

Was tetracycline taken off the market?

These drugs are no longer on the market, but there are currently four tetracycline antibiotic derivatives available on the United States drug market. Tetracycline is a naturally occurring molecule derived from Streptomyces bacteria.

What is the side effect of tetracycline?

Nausea, vomiting, diarrhea, loss of appetite, mouth sores, black hairy tongue, sore throat, dizziness, headache, or rectal discomfort may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Can antibiotics turn teeth Gray?

Tetracycline and Gray Teeth

Tetracycline is an antibiotic medication designed to fight bacterial infections in your body, such as urinary tract infections, acne and other infections, that has been proven to cause tooth discoloration.

Does zoom work on tetracycline stained teeth?

Clinical significance: Because tetracycline staining may respond to bleaching treatments based on the photo-Fenton reaction, systems, such as Zoom! WhiteSpeed, may have benefits as adjuncts to home bleaching for patients with tetracycline-staining.

Does tetracycline cause skin discoloration?

Hyperpigmentation of the skin, nails, thyroid, oral mucosa, teeth, and bones is a known but rare side effect of prolonged tetracycline use. The hyperpigmentation typically takes months to years to develop. There may also be residual changes to the skin after discontinuation of the medication.

Does tetracycline cause nerve damage?

Several factors are suggestive of a toxic effect of tetracycline on the peripheral nervous system in our patient. There is a time association between development of neuronopathy and the tetracycline treatment. No obvious other cause of the neuronopathy was found despite extensive evaluation.

What are some of the side effects of tetracycline and when is it contraindicated?

Who should not take TETRACYCLINE HCL?
  • diarrhea from an infection with Clostridium difficile bacteria.
  • pseudotumor cerebri, a condition with high fluid pressure in the brain.
  • liver problems.
  • decreased kidney function.
  • pregnancy.

Can antibiotics cause dark skin?

Hyperpigmentation and Skin

Hyperpigmentation can also be caused by various drugs, including some antibiotics, antiarrhythmics, and antimalarial drugs.

Which antibiotics cause bruise discoloration?

Penicillins and cephalosporin antibiotics like cephalexin, cefaclor and cefuroxime-axetil are commonly prescribed antibiotics, and are a rare cause of easy bruising as taking them can result in a low platelet count.

Does isoniazid cause skin darkening?

Nonsteroidal anti-inflammatory drugs, antimalarials, amiodarone, cytotoxic drugs, tetracyclines, heavy metals and psychotropic drugs are most commonly responsible for hyperpigmentation. A 74-year-old man who had taken antituberculosis drugs (rifampin and isoniazid) for 4 months developed generalized hyperpigmentation.

Can antibiotics change skin color?

Skin color changes can be caused by medications including: Acne preparations. Antibiotics.

What medications cause discoloration?

The main drugs implicated in causing skin pigmentation are nonsteroidal anti-inflammatory drugs, antimalarials, amiodarone, cytotoxic drugs, tetracyclines, heavy metals and psychotropic drugs.

How do you stop skin discoloration?

How to prevent hyperpigmentation
  1. Avoid direct sunlight. Try to stay out of the sun during the peak hours of 10 am to 2 pm. …
  2. Use a hat. Shade your face and scalp with a wide-brimmed hat.
  3. Incorporate Vitamin C into your beauty routine. …
  4. Apply SPF. …
  5. Limit touching your skin.

Why is my skin changing colors?

Some of the more common causes for changes in skin color are illness, injury, and inflammatory problems. Discolored skin patches also commonly develop in a certain part of the body due to a difference in melanin levels. Melanin is the substance that provides color to the skin and protects it from the sun.