How do I make LINZESS work better?

Taking your prescribed dose every morning 30 minutes before your first meal of the day will make a big difference in how well Linzess works for you. If you miss a dose of Linzess, skip the dose you missed and take the next dose the following day before your first meal.

Will LINZESS work on a full stomach?

Take this medication by mouth on an empty stomach as directed by your doctor, usually once daily at least 30 minutes before your first meal of the day. Swallow the capsules whole. Do not break or chew the capsules.

What happens when you take LINZESS with food?

Taking linaclotide with food may increase gastrointestinal side effects such as diarrhea, abdominal pain, and gas. The absorption of any other oral medication you may take can be affected if you develop frequent or severe diarrhea.

How long after taking LINZESS can I eat?

Take LINZESS exactly as your doctor tells you to take it. the day. You should also wait 30 minutes before eating a meal if you take LINZESS with applesauce or mixed with water.

Is it better to take LINZESS in the morning or at night?

Consuming Linzess (linaclotide) at night is not recommended. The best time to take Linzess is in the morning (on an empty stomach), half an hour before breakfast. Consumption of Linzess with food may lead to several gastrointestinal side effects, including gas, diarrhoea, and abdominal pain.

How much water should you drink with LINZESS?

WITH APPLESAUCE OR WATER, IF NECESSARY If you have trouble swallowing capsules, carefully open the LINZESS capsule and sprinkle all of the LINZESS beads onto applesauce or into 1 oz. (30mL) of water.

Do I take LINZESS with a glass of water?

For adult patients with swallowing difficulties, LINZESS capsules can be opened and administered orally in either applesauce or with water or administered with water via a nasogastric or gastrostomy tube.

What time of day is best to take LINZESS?

WHAT IS THE BEST TIME OF DAY TO TAKE LINZESS? Take LINZESS on an empty stomach, at least 30 minutes before your first meal of the day. Remember to take LINZESS daily, as prescribed by your doctor, to proactively manage your symptoms.

Can I drink coffee while taking LINZESS?

Fried and fatty foods, along with alcohol and caffeinated beverages like coffee and soda, may worsen your symptoms and should be avoided.

Can I take miralax and Linzess together?

Miralax should not be taken with Linzess because the combination can increase the risk of dehydration and electrolyte abnormalities. Miralax also should not be taken with Trintellix or Fetzima because the combination may increase the risk of SIADH or low sodium.

Is Linzess better than miralax?

Polyethylene glycol (Miralax) is preferred over lactulose for the treatment of constipation because it is more effective and has fewer adverse effects. Linaclotide (Linzess) and lubiprostone (Amitiza) are more effective than placebo for chronic constipation.

Is Linzess a laxative or stool softener?

LINZESS isn’t a laxative. It helps you have more frequent and complete bowel movements, and helps relieve belly pain and overall abdominal symptoms* (pain, discomfort, and bloating) associated with IBS-C.

What laxatives can I take with Linzess?

Laxatives (like MiraLax®, Phillips’® Milk of Magnesia, or Dulcolax®) Fiber products (such as Metamucil®) Stool softeners (like Colace®)

Can you take milk of magnesia with Linzess?

Linzess (linaclotide) Milk of Magnesia (magnesium hydroxide)

Drug Interaction Classification.
MajorHighly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
ModerateModerately clinically significant. Usually avoid combinations; use it only under special circumstances.

Can you drink alcohol with Linzess?

The potential interactions of Linzess and alcohol are not well established. Drinking alcohol while taking this medication may increase the risk for adverse effects. Alcohol may also increase your symptoms of IBC-C and CIC. For these reasons, avoid drinking alcohol while taking Linzess.

Can you take omeprazole and Linzess at the same time?

This report displays the potential drug interactions for the following 2 drugs: Linzess (linaclotide)

Drug Interaction Classification.
MajorHighly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
UnknownNo interaction information available.

Can Linzess cause bowel obstruction?

Linaclotide (applies to Linzess) gastrointestinal obstruction. Major Potential Hazard, High plausibility. The use of linaclotide is contraindicated in patients with known or suspected mechanical gastrointestinal obstruction. Because linaclotide accelerates gastrointestinal transit, it can exacerbate a blockage.

What is comparable to Linzess?

Compare Linzess alternatives
Compare Linzess alternatives
Amitiza (lubiprostone)IBS-C in women ages 18 years and older CIC in adults Opioid-induced constipation (OIC) in adults with chronic pain not due to cancerGet Amitiza coupons
Bentyl (dicyclomine)Functional bowel or irritable bowel syndromeGet Bentyl coupons
Feb 17, 2022

Can LINZESS be cut in half?

Capsules should be swallowed whole and not chewed or crushed. There’s more than one way to take LINZESS.

Can I take LINZESS and Synthroid together?

Interactions between your drugs

Linaclotide may cause diarrhea, which may affect the absorption of any other oral medication you may take. If you develop diarrhea, some of your medications such as levothyroxine may not work as well.

Does LINZESS cause acid reflux?

Defecation urgency, fecal incontinence, vomiting, and gastroesophageal reflux disease were reported in <2% of patients in the LINZESS-treatment group and at an incidence greater than in the placebo treatment group.

Are there different strengths of LINZESS?

LINZESS is available as 72 mcg, 145 mcg and 290 mcg capsules for oral administration.