Hydroxyl (B1-B6-B12): functions and side effects of this drug
Our body is a conglomerate of systems and organs integrated and organized in an effective and efficient way, being its functioning what allows our survival and adaptation to the environment. For such functioning it is neither self-sufficient nor eternal, needing our organism of great amount of oxygen and nutrients. Among the latter, we can find different types of vitamins, essential for a large number of body systems.
The absence of these vitamins , either because we do not integrate enough of them into our diet or because of some pathology, can have consequences of variable severity and in multiple body systems, such as weakness, appearance of inflammations or pain.
Fortunately we have different drugs and supplements that can help to try to fill a specific deficiency or increase the amounts of some vitamins present in the body that may have a beneficial effect on some ailment. This is the case of Hydroxyl B1-B6-B12, which we will talk about next .
What is Hydroxyl B1-B6-B12?
It is called Hidroxil B1-B6-B12 a medicine composed of different vitamins of the B group and is used mainly in states of deficiency of these vitamins or for certain problems related to pain and inflammation of nerve tracts, being indicated for people over twelve years of age.
Specifically, this is a drug in the form of film-coated tablets that is mainly made up of vitamins B1, B6 and B12, also known as thiamin hydrochloride (B1), pyridoxine hydrochloride (B6) and cyanocobalamin (B12). This group of vitamins is associated with the metabolism of carbohydrates and proteins , being especially associated with that produced in the nervous and neuroendocrine system.
Thus, this drug has a certain modulating effect that can alter the functioning of various neurotransmitters in addition to promoting health and the transmission of information (it is also related to the synthesis of the myelin that covers the neurons) of these systems. Likewise, its association has an influence on the transmission of information related to the perception of pain at both thalamic and spinal levels, something that makes it have the property of mediating and reducing the level of pain of various conditions.
What’s it for? Main functions
Hydroxyl B1-B6-B12 is, as we have just mentioned, a drug that has repercussions at the level of the nerve tracts , many of the main indications of this drug being deeply linked to this system.
It is considered that Hydroxyl is especially indicated in those people who have some type of anemia with deficiency of group B vitamins , as well as in those conditions in which a state of convalescence and weakness is present. Another possible indication is the presence of asthenia, generally related to the previous symptomatology, and fatigue.
It is also indicated for low back pain or sciatica, as well as for the effects derived from neuritis and other neuropathies, given its effects on pain modulation and different neurotransmitters.
Side effects and contraindications
Hydroxyl B1-B6-B12 is a compound formed mainly by vitamins of the B group, something that may seem at first to be totally healthy and harmless. However, an excess of these vitamins in our body can be harmful and have severe side effects .
As secondary symptoms it has been observed that the drug can cause dizziness and agitation, headaches, as well as conjunctivitis, tingling, drowsiness or insomnia, diarrhea or loss of appetite. It can generate changes in the colouring of the urine, because its high content in vitamins can generate renal or hepatic problems or alterations. Also photosensitivity with skin rashes, dermatitis may appear.
In some cases, purple thrombocytopenia (a deficit of platelets in the blood that makes coagulation difficult) or the appearance of rosacea fulminans have been observed, in addition to increasing the risk of contracting gout. In the case of vitamin B6, excessive or very prolonged consumption may be toxic at the neuronal level, and may lead to peripheral sensory neuropathy (a condition linked to loss of sensation in the extremities and peripheral nerves).
It can also generate memory disorders, autoimmune problems and effects on the visual system . It has also been linked to the appearance of rosacea fulminans, in addition to increasing the risk of contracting gout and potentially generating respiratory difficulties. In rare cases, a severe allergic reaction or a decrease in folic acid may occur.
Due to these side effects, Hydroxyl has several conditions in which it is contraindicated. The first of them and perhaps the most obvious is the case of all those people who present an allergy or hypersensitivity to any of its components. Besides, it should not be taken by people with renal or hepatic problems, as well as by the population under twelve years old.
It is totally contraindicated also in pregnancy and lactation , since it can alter the nervous function and the proprioception of the fetus, generate dependency in it or even cut off lactation. If any other medication is taken continuously, the doctor should be consulted about the suitability of continuing to take this drug, since it presents numerous interactions with different groups of medications. It should also be avoided in conjunction with alcohol or other drugs.
Bibliographic references:
- Vidal Vademecum Spain (2016). HIDROXIL B1-B6-B12 Film coated comp. [Online]. Available at: https://www.vademecum.es/medicamento-hidroxil+b1-b6-b12_44109.